Demarcating SurA Activities Required for Outer Membrane Targeting of Yersinia pseudotuberculosis Adhesins
نویسندگان
چکیده
منابع مشابه
Characterization of outer membrane proteins of Yersinia pestis and Yersinia pseudotuberculosis strains isolated from India.
The majority of virulence factors including the 12 Yersinia outer membrane proteins (Yops), 29 Yop secretion proteins (Ysc) and few specific Yop chaperone (Syc) are contributed by the 70 kb LCR middle plasmid of Yersinia pestis. Yersinia pestis isolates recovered during 1994 plague outbreak and rodent surveillance samples of Southern states of India were studied for the presence of important Yo...
متن کاملComponents of SurA Required for Outer Membrane Biogenesis in Uropathogenic Escherichia coli
BACKGROUND SurA is a periplasmic peptidyl-prolyl isomerase (PPIase) and chaperone of Escherichia coli and other Gram-negative bacteria. In contrast to other PPIases, SurA appears to have a distinct role in chaperoning newly synthesized porins destined for insertion into the outer membrane. Previous studies have indicated that the chaperone activity of SurA rests in its "core module" (the N- plu...
متن کاملImmunochemical Properties of Recombinant Ompf Porin from Outer Membrane of Yersinia pseudotuberculosis
Porins from outer membranes (OM) of Gram-negative bacteria exist in intact membranes as homotrimers forming water-filled pores or channels that provide low-molecular compounds transportation. Surface localization of the porins and their structural peculiarities determine multiplicity of their functions except for the transport one. On the one hand, porins are targets for the host immune system....
متن کاملMolecular cloning of the temperature-inducible outer membrane protein 1 of Yersinia pseudotuberculosis.
When Yersinia pseudotuberculosis is shifted from growth at 26 degrees C to growth at 37 degrees C, the synthesis of a plasmid-associated outer membrane protein, protein 1, is induced (Bölin et al., Infect. Immun. 37:506-512). The structural gene of this protein was found to be located on the virulence plasmid pIB1 of Y. pseudotuberculosis. One cosmid hybrid plasmid pBW8 was studied which carrie...
متن کاملThe membrane localization domain is required for intracellular localization and autoregulation of YopE in Yersinia pseudotuberculosis.
Recent work has shown that a domain of YopE of Yersinia pseudotuberculosis ranging from amino acids 54 to 75 (R. Krall, Y. Zhang, and J. T. Barbieri, J. Biol. Chem. 279:2747-2753, 2004) is required for proper localization of YopE after ectopic expression in eukaryotic cells. This domain, called the membrane localization domain (MLD), has not been extensively studied in Yersinia. Therefore, an i...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2013
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.01208-12